The Brooks Adrenaline GTS 25 and the Brooks Glycerin GTS 22 are the two flagship stability shoes in the Brooks range. Both offer guidance for people who need support, but they achieve this stability in very different ways. As a result, they feel completely different underfoot whether you’re walking, running, or choosing a shoe for a particular foot condition.
In this review, I break down the cushioning, support systems, fit, and performance so you know which model is the best choice for your needs.
Cushioning: Balanced vs. Bouncy
The first noticeable difference is the type of cushioning used in each shoe.
Brooks Adrenaline GTS 25 – DNA Loft v3
The Adrenaline uses DNA Loft v3, which offers a balanced, slightly firmer feel.
This gives you:
- Smooth transitions
- Good ground feel
- Less bounce underfoot
It’s predictable and stable but not particularly energetic.
Brooks Glycerin GTS 22 – DNA Tuned Nitrogen-Infused Foam
The Glycerin GTS 22 uses DNA Tuned cushioning — a nitrogen-infused foam first seen in the Glycerin Max.
It features:
- Larger cells in the heel for softer landings
- Tighter-packed cells in the forefoot for a springy push-off
This creates a noticeably bouncier ride with more cushioning depth and responsiveness than the Adrenaline.
Stack Height Comparison
| Model | Heel Stack | Forefoot Stack | Drop |
|---|---|---|---|
| Glycerin GTS 22 | 39 mm | 29 mm | 10 mm |
| Adrenaline GTS 25 | 37 mm | 27 mm | 10 mm |
The Glycerin is 2 mm higher in both heel and forefoot, giving it a softer, slightly more protective forefoot feel.
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Forefoot Feel & Flexibility
The cushioning setups influence how the forefoot behaves during push-off:
- Adrenaline GTS 25 → More flexible forefoot
- Glycerin GTS 22 → Slightly stiffer forefoot
A firmer, more flexible forefoot (Adrenaline) can increase pressure through the big toe and metatarsals in some people. A stiffer forefoot (Glycerin) tends to reduce excessive bending of the toes, which can be helpful for people with forefoot sensitivity or mild toe-joint issues.
Stability Systems: Subtle vs. Prominent Support
Both shoes use Brooks’ Go-To Support (GTS) system, but the execution is completely different.
Glycerin GTS 22 – Direct Arch Support
- The guide rail foam is more prominent.
- It runs along the inside of the shoe and rises higher into the arch.
- You can feel this support in the heel and midfoot.
This is ideal if you prefer a shoe that feels like it is actively supporting your arch.
Adrenaline GTS 25 – Minimalist, Centred Support
Brooks modified the GTS design in this version:
- Less intrusive arch pressure
- Larger sidewalls rather than a raised arch
- The shoe focuses on keeping you centred rather than pushing up into the arch
This is great for runners or walkers who want support without feeling it.
Platform Differences
- Both have a wide base, but the Glycerin’s base is slightly wider, adding inherent stability.
- Both feature sole flare, meaning the midsole extends wider than the foot for lateral support.
Fit and Upper Construction
Glycerin GTS 22
- Slightly wider fit
- More room for toes to splay
- Soft engineered mesh
- Plush padding around the collar
- Very comfortable on first step-in
Adrenaline GTS 25
- More traditional athletic fit
- Updated pull tab at the heel
- Engineered mesh with good structure
- Plush tongue and collar without being overly padded
Both models offer a premium fit, but the Glycerin has the edge in toe-box width and overall softness.
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Weight & Daily Use
| Model | Weight (Men’s US 9) |
|---|---|
| Glycerin GTS 22 | 303 g |
| Adrenaline GTS 25 | 289 g |
The Glycerin is heavier, but the difference is small — during walking you are unlikely to notice it.
Both shoes use a 10 mm drop, which is slightly lower than the previous Adrenaline version. High-drop shoes can sometimes place more pressure through the forefoot, especially in people with:
- Capsulitis
- Metatarsalgia
- Sesamoid irritation
- Big toe joint sensitivity
In these cases, the stiffer forefoot and extra width of the Glycerin may feel more protective than the flexible forefoot of the Adrenaline.
Performance: Which Shoe Works Best for Running?
Both shoes work well for:
- Easy runs
- Recovery days
- Daily training
- Long walks
- Distances up to half marathon pace
However, their strengths differ:
Glycerin GTS 22 – Max Stability + Premium Cushioning
Best for runners who want:
- More noticeable arch support
- Softer landings
- A bouncier push-off
- A more cushioned forefoot
This is the more protective and supportive shoe overall.
Adrenaline GTS 25 – Light, Balanced, Subtle Support
Ideal for runners who prefer:
- Firmer cushioning
- A flexible forefoot
- Lower-profile support
- A slightly lighter shoe
This feels more like a traditional stability trainer.
Comparison Table: Brooks Adrenaline GTS 25 vs Glycerin GTS 22
| Feature | Adrenaline GTS 25 | Glycerin GTS 22 |
|---|---|---|
| Cushioning | DNA Loft v3 (balanced, firmer) | DNA Tuned nitrogen-infused (bouncy) |
| Heel / Forefoot | 37 mm / 27 mm | 39 mm / 29 mm |
| Drop | 10 mm | 10 mm |
| Forefoot Flex | More flexible | Stiffer / more protective |
| Stability Feel | Subtle sidewall guidance | Prominent arch-level guide rails |
| Base Width | Wide | Slightly wider |
| Fit | Standard | Roomier toe box |
| Weight | 289 g | 303 g |
| Best For | Mild–moderate stability needs | Moderate–high stability needs |
| Ride Feel | Smooth, firm, stable | Soft, cushioned, springy |
Medical Considerations
Both shoes are suitable for stability needs, but they suit different patterns:
- Glycerin GTS 22: Better for people who want more structure through the arch, or who benefit from a slightly stiffer forefoot.
- Adrenaline GTS 25: Better for people who prefer minimal arch pressure or who react poorly to firmer support systems.
Final Thoughts
Both the Adrenaline GTS 25 and Glycerin GTS 22 are excellent stability shoes, but they cater to different preferences. If you want softness, bounce, and more visible guidance, the Glycerin is the standout. If you prefer firmer cushioning and subtle support, the Adrenaline remains one of the most reliable daily trainers on the market.
Let me know which one you prefer — and how they feel for your foot type.
Medical Disclaimer
This article is intended for educational purposes only and does not replace personalised medical advice. If you have ongoing foot pain or a diagnosed condition, consult a qualified healthcare professional for assessment and individual guidance.
