Brooks Glycerin 22 vs Adrenaline GTS 24 Review

Hi, I’m James, a foot and ankle specialist, and today I’m breaking down the key differences between two standout shoes in the Brooks lineup: the Brooks Adrenaline GTS 24 and the Brooks Glycerin 22. Whether you’re looking for a neutral daily trainer or a stability-focused shoe, this review will help you decide which one suits your needs.


Midsole Comparison: DNA Loft V3 vs. DNA Tuned Cushioning

The Glycerin 22 features Brooks’ all-new DNA Tuned Nitrogen-Infused Midsole, which is softer, more plush, and springier than its predecessor. It’s designed with:

  • Larger cells in the rearfoot for absorbing impact and vibration during heel or midfoot strikes.
  • Densely packed cells in the forefoot to provide springy propulsion during the gait cycle.

In comparison, the Adrenaline GTS 24 comes with the DNA Loft V3 Nitrogen-Infused Midsole, which offers balanced cushioning. It’s firmer than the Glycerin 22, providing better ground feel and less sinking into the shoe. While the GTS focuses on balanced shock absorption, the Glycerin 22 feels softer and more cushioned underfoot, making it a standout for long, comfortable runs.

If you’re curious about similar innovations, check out our review of the Brooks Glycerin Max, which also features DNA Tuned Cushioning but with a higher stack height for max comfort.


Stability vs. Neutral Design

  • Adrenaline GTS 24:
    This is a moderate-to-maximum stability shoe featuring Brooks’ GuideRails® Support System, which:
    • Includes denser foam on the medial side to resist pronation forces and guide the foot back into alignment.
    • It offers a wide base with sole flare in the forefoot to keep the foot centred.
    • It ensures stability with sidewalls and a moderately stiff heel counter, making it an excellent choice for those who overpronate or need added support.
  • Glycerin 22:
    This is a classic neutral shoe with:
    • Sidewalls for mild stability, particularly in the heel and midfoot.
    • It has a softer feel underfoot, making it ideal for recovery runs or long-distance cruising.
    • A mild stiffness in the heel counter that adds slight support without altering the neutral design.

If you’re seeking a more stability-focused option for faster workouts, you might explore the Hoka Arahi 7, another standout in the moderate stability category.

Picture of the Brooks Glycerin 22 from the side in blue at annecy lake

Weight and Drop

Both shoes maintain Brooks’ traditional 10mm drop, but they differ slightly in weight:

  • Adrenaline GTS 24: 283g (Men’s US Size 9)
  • Glycerin 22: 289g (Men’s US Size 9)

The slight weight difference reflects the Glycerin’s plush cushioning versus the GTS’s stability features.


Upper Design

Both shoes offer engineered mesh uppers, but the Glycerin 22 stands out with its:

  • Creel Jacquard Mesh, which feels more luxurious and wraps the foot for a snug fit.
  • Thin outer collar and padded heel collar with an extenal tab for easy slip-on functionality. Similar in look and feel to the Gel-Nimbus 26.

The Adrenaline GTS 24 has a more straightforward engineered mesh upper, with a padded tongue and heel counter that offer a secure fit. Both shoes come in standard, wide, and extra-wide widths to accommodate various foot shapes.


Intended Use

  • Brooks Glycerin 22:
    • Best for recovery runs, long-distance running, and steady, comfortable daily use.
    • Its plush, springy midsole makes it perfect for runners who want a soft ride.
  • Brooks Adrenaline GTS 24:
    • Designed for day-to-day walking, standing, and moderate to long-distance running.
    • Its balanced cushioning and stability features make it a versatile option for those who overpronate or need extra support.

If you’re seeking an all-rounder stability shoe with similar functionality, check out the Asics GT-2000 13, which offers a slightly firmer ride.

Picture of the Brooks Adrenaline GTS 24 from the side at Annecy lake

Which Should You Choose?

  • Choose the Glycerin 22 if you prioritise plush cushioning and a softer, more springy ride.
  • Opt for the Adrenaline GTS 24 if you need moderate to maximum stability for overpronation or prefer a firmer, more balanced feel underfoot.

Final Thoughts

The Glycerin 22’s DNA Tuned Cushioning is a game-changer for runners seeking plush comfort, while the Adrenaline GTS 24 continues to shine as a stability favourite. Both are excellent shoes, but their distinct features cater to different needs.

We’ve included links to both shoes throughout the article. Purchasing through these links helps support the channel at no extra cost to you. If you found this comparison helpful, don’t forget to like, share, and subscribe for more detailed reviews. Leave any questions in the comments, and we’ll get back to you.

Thank you for reading, and happy running!

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